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Antibiotics were first massed-produced in the 1940s. Their ability to fight and kill bacteria revolutionized medicine and had profound effects on everything from agriculture to war. After less than 80 years, however, these miracle drugs are failing. Resistant infections kill hundreds of thousands of people around the world each year, and there are now dozens of so-called Superbugs each with its own challenges and costs. How did this happen? Using microscopic footage, harrowing personal stories, and expert insights RESISTANCE clarifies the problem of antibiotic resistance, how we got to this point, and what we can do to turn the tide.